Figure 1c: No. of UMRs between MZ twins and neurospheres
No. of UMRs (hypermethylated in red and hypomethylated in blue) between monozygotic twins and Cortex vs GE neurospheres.
No. of UMRs between MZ twins are on the same scale as UMRs between neurospheres.
## pdf
## 2
Figure 1d: UMR/DE genes accumulates over time
## pdf
## 2
Figure 2: Neurospheres Cortex and GE
Figure 2a: TFBS asymmetry between neurosphere UMRs
Figure 2b: GREAT enrichment for neurospheres UMRs
Supplemental Figures
Supplemental 1: Asymmetry in UMRs between MZ twins in Brain and Cortex
UMR frequency (base pair per million base pair) between MZ twins (HuFNSC01 UMRs in blue, and HuFNSC02 UMRs in red) in Brain, Neurospheres Cortex derived and GE derived across different chormosomes.
## pdf
## 2
Supplemental 2: Genomic breakdown of UMRs
## pdf
## 2
Supplemental 3: Fraction of DE genes with proximal UMRs
## pdf
## 2
Supplemental 4: Differential expressed genes between MZ twins are cell type specific
No. of differential expressed genes between MZ twins in Brain (green), Neurospheres Cortex derived (red), and GE derived (blue).
## pdf
## 2
Supplemental 5: DAVID enrichment for MZ DE genes
Supplemental 6: Validate WGBS UMRs with MeDIP/MRE
Supplemental 7: Location of UMRs across the genome
## pdf
## 2
Supplemental 8: Neurosphere UMR enrichemnt at chromosome ends
Supplemental 9: UMR asymmetry between Cortex and GE with MeDIP
Supplemental 10: GREAT enrichment for neurospheres UMRs with MeDIP
Supplemental 11: DAVID enrichment for neurospheres DE genes
Supplemental 12: DAVID enrichment for neurospheres isoform genes
Supplemental 13: TFBS asymmetry in MZ UMRs
Supplemental 14: DNA methylation at exon boundaries
## pdf
## 2
Supplemental 15: DNA methylation at exon boundaries with MeDIP
## pdf
## 2
Supplemental 16: Expression of DNA methylation reulators